SYNTHESIS OF 3'-AMINO-3'-DEOXYADENOSINE DERIVATIVES AS POTENTIAL-DRUGS FOR THE TREATMENT OF MALARIA

被引：6

作者：

SOENENS, J

FRANCOIS, G

VANDENEECKHOUT, E

HERDEWIJN, P

机构：

[1] INST TROP MED PRINCE LEOPOLD,PROTOZOOL LAB,B-2000 ANTWERP,BELGIUM

[2] STATE UNIV GHENT,FAC PHARMACEUT SCI,DEPT MED CHEM,B-9000 GHENT,BELGIUM

来源：

NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期

关键词：

D O I：

10.1080/15257779508012396

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A series of 3'-substituted 3'-amino-3'-deoxyadenosine analogues were synthesized and subsequently tested against the human malaria parasite Plasmodium falciparum in vitro. Several amongst them displayed pronounced antiplasmodial activities.

引用

页码：409 / 411

页数：3

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