SYNTHESIS OF 3'-AMINO-3'-DEOXYADENOSINE DERIVATIVES AS POTENTIAL-DRUGS FOR THE TREATMENT OF MALARIA

被引：6
作者：
SOENENS, J
FRANCOIS, G
VANDENEECKHOUT, E
HERDEWIJN, P
机构：
[1] INST TROP MED PRINCE LEOPOLD,PROTOZOOL LAB,B-2000 ANTWERP,BELGIUM
[2] STATE UNIV GHENT,FAC PHARMACEUT SCI,DEPT MED CHEM,B-9000 GHENT,BELGIUM
来源：
NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期
关键词：
D O I：
10.1080/15257779508012396
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A series of 3'-substituted 3'-amino-3'-deoxyadenosine analogues were synthesized and subsequently tested against the human malaria parasite Plasmodium falciparum in vitro. Several amongst them displayed pronounced antiplasmodial activities.
引用
收藏
页码：409 / 411
页数：3
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