A MATHEMATICAL-MODEL OF FLOW-THROUGH THE TERMINAL LYMPHATICS

被引：32

作者：

REDDY, NP

PATEL, K

机构：

[1] Department of Biomedical Engineering, University of Akron, Akron

来源：

MEDICAL ENGINEERING & PHYSICS | 1995年 / 17卷 / 02期

关键词：

LYMPHATIC SYSTEM; TERMINAL LYMPHATICS; MATHEMATICAL MODEL;

D O I：

10.1016/1350-4533(95)91885-K

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Proper understanding of the mechanisms of fluid absorption and flow through the terminal lymphatics is essential for the control of several Pathological conditions such as edema, bedsores and cancer. A mathematical model of the terminal lymphatics was developed using the principles of mechanics. Computer simulation results substantiate the hypothesis that fluid absorption and flow through the terminal lymphatics occur due to suction mechanisms of the adjacent contractile lymphatic segments and due to periodic fluctuations in the interstitial fluid pressure. In addition, the results suggested that increasing the length of a terminal lymphatic vessel beyond a certain limit does not cause further increase in fluid flow into the terminal lymphatic.

引用

页码：134 / 140

页数：7