Cystoid Macular Edema Due to Accidental Latanoprost Overdose After Uncomplicated Phacoemulsification

被引：5

作者：

Makri, Olga E. ^{[1
]}

Tsekouras, Iasonas K. ^{[1
]}

Plotas, Panagiotis ^{[1
]}

Tsapardoni, Foteini ^{[1
]}

Pallikari, Athina ^{[1
]}

Georgakopoulos, Constantine D. ^{[1
]}

机构：

[1] Univ Patras, Sch Med, Dept Ophthalmol, Patras 26504, Greece

来源：

CURRENT DRUG SAFETY | 2018年 / 13卷 / 03期

关键词：

Cystoid macular edema; uneventful phacoemulsification; latanoprost overdose; rechallenge; prostaglandin analogues; best corrected visual acuity; optical coherence tomography;

D O I：

10.2174/1574886313666180619163845

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Objective: We present an interesting case of accidental overdose of latanoprost eye drops. Case Report: A 71-year-old patient underwent an uncomplicated cataract surgery in his right eye. During the first postsurgical week he mistakenly used latanoprost eye drops six times daily instead of the prescribed tobramycin/dexamethasone eye drops. The patient experienced gradually decreasing visual acuity and was diagnosed with cystoid macular edema seven weeks after surgery. The cystoid macular edema resolved 4 weeks later after treatment with nepafenac 0.3% eye drops and oral acetazolamide. The cystoid macular edema recurred 2 weeks after rechallenge with latanoprost. The rechallenge-induced cystoid macular edema once again resolved after cessation of latanoprost and retreatment with nepafenac eye drops. A Naranjo assessment score of 7 was obtained, indicating a probable relationship between the patient's symptoms and the suspect drug.

引用

页码：208 / 210

页数：3

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