Systemic in vivo antitumor activity of interleukin-12 against both transplantable and primary tumor

被引：14
作者：
Nishimura, T
Watanabe, K
Lee, U
Yahata, T
Ando, K
Kimura, M
Hiroyama, Y
Kobayashi, M
Herrmann, SH
Habu, S
机构：
[1] TOKAI UNIV,SCH MED,DEPT INFECT DIS,ISEHARA,KANAGAWA 25911,JAPAN
[2] TOKAI UNIV,SCH MED,DEPT MOLEC LIFE SCI,ISEHARA,KANAGAWA 25911,JAPAN
[3] DNARD INC,KAWASAKI,KANAGAWA 216,JAPAN
[4] GENET INST INC,CAMBRIDGE,MA 02140
来源：
IMMUNOLOGY LETTERS | 1995年 / 48卷 / 02期
关键词：
interleukin-12; tumor immunotherapy; primary tumor; mouse;
D O I：
10.1016/0165-2478(95)02448-4
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
[No abstract available]
引用
收藏
页码：149 / 152
页数：4
相关论文
共 50 条
  • [21] Activation of mononuclear cells by interleukin-12:: An in vivo study in chimpanzees
    Lauw, FN
    Te Velde, AA
    Dekkers, PEP
    Speelman, P
    Aerts, JMFG
    Hack, CE
    Van Deventer, SJH
    Van der Poll, T
    JOURNAL OF CLINICAL IMMUNOLOGY, 1999, 19 (04) : 231 - 238
  • [22] Activation of Mononuclear Cells by Interleukin-12: An In Vivo Study in Chimpanzees
    Fanny N. Lauw
    Anje A. Te Velde
    Pascale E. P. Dekkers
    Peter Speelman
    Johannes M. F. G. Aerts
    C. Erik Hack
    Sander J. H. Van Deventer
    Tom Van Der Poll
    Journal of Clinical Immunology, 1999, 19 : 231 - 238
  • [23] Interleukin-12 inhibits eotaxin secretion of cultured primary lung cells and alleviates airway inflammation in vivo
    Ye, YL
    Huang, WC
    Lee, YL
    Chiang, BL
    CYTOKINE, 2002, 19 (02) : 76 - 84
  • [24] Oncolytic adenovirus coexpressing interleukin-12 and shVEGF restores antitumor immune function and enhances antitumor efficacy
    Ahn, Hyo Min
    Hong, JinWoo
    Yun, Chae-Ok
    ONCOTARGET, 2016, 7 (51): : 84965 - 84980
  • [25] Retroviral-mediated transfer of genes encoding interleukin-2 and interleukin-12 into fibroblasts increases host antitumor responsiveness
    Anne-Sophie Govaerts
    Thierry Guillaume
    Marc André
    Babak Bayat
    Anne-Marie Feyens
    Teresa S Hawley
    A Z C Fong
    Robert G Hawley
    Michel Symann
    Cancer Gene Therapy, 1999, 6 : 447 - 455
  • [26] Augmented antitumor effects of combination therapy with interleukin-12, cisplatin, and tumor necrosis factor-α in a murine melanoma model
    Zagozdzon, R
    Stoklosa, T
    Golab, J
    Giermasz, A
    Dabrowska, A
    Lasek, W
    Jakóbisiak, M
    ANTICANCER RESEARCH, 1997, 17 (6D) : 4493 - 4498
  • [27] Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12
    Mazzolini, G
    Narvaiza, I
    Pérez-Diez, A
    Rodriguez-Calvillo, M
    Qian, C
    Sangro, B
    Ruiz, J
    Prieto, J
    Melero, I
    GENE THERAPY, 2001, 8 (04) : 259 - 267
  • [28] Retroviral-mediated transfer of genes encoding interleukin-2 and interleukin-12 into fibroblasts increases host antitumor responsiveness
    Govaerts, AS
    Guillaume, T
    André, M
    Bayat, B
    Feyens, AM
    Hawley, TS
    Fong, AZC
    Hawley, RG
    Symann, M
    CANCER GENE THERAPY, 1999, 6 (05) : 447 - 455
  • [29] Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12
    G Mazzolini
    I Narvaiza
    A Pérez-Diez
    M Rodriguez-Calvillo
    C Qian
    B Sangro
    J Ruiz
    J Prieto
    I Melero
    C Quian
    Gene Therapy, 2001, 8 : 259 - 267
  • [30] Induction of an antitumor immunological response by an intratumoral injection of dendritic cells pulsed with genetically engineered Semliki Forest virus to produce interleukin-18 combined with the systemic administration of interleukin-12
    Yamanaka, R
    Tsuchiya, N
    Yajima, N
    Honma, J
    Hasegawa, H
    Tanaka, R
    Ramsey, J
    Blaese, RM
    Xanthopoulos, KG
    JOURNAL OF NEUROSURGERY, 2003, 99 (04) : 746 - 753
12345