Systemic in vivo antitumor activity of interleukin-12 against both transplantable and primary tumor

被引:14
作者
Nishimura, T
Watanabe, K
Lee, U
Yahata, T
Ando, K
Kimura, M
Hiroyama, Y
Kobayashi, M
Herrmann, SH
Habu, S
机构
[1] TOKAI UNIV,SCH MED,DEPT INFECT DIS,ISEHARA,KANAGAWA 25911,JAPAN
[2] TOKAI UNIV,SCH MED,DEPT MOLEC LIFE SCI,ISEHARA,KANAGAWA 25911,JAPAN
[3] DNARD INC,KAWASAKI,KANAGAWA 216,JAPAN
[4] GENET INST INC,CAMBRIDGE,MA 02140
关键词
interleukin-12; tumor immunotherapy; primary tumor; mouse;
D O I
10.1016/0165-2478(95)02448-4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:149 / 152
页数:4
相关论文
共 50 条
  • [1] Antitumor activity of interleukin-12 against murine bladder cancer
    Eto, M
    Harada, M
    Tamada, K
    Tokuda, N
    Koikawa, Y
    Nakamura, M
    Nomoto, K
    Naito, S
    JOURNAL OF UROLOGY, 2000, 163 (05) : 1549 - 1552
  • [2] Antitumor activity of killer cells stimulated with both interleukin-2 and interleukin-12 on mouse glioma cells
    Kikuchi, T
    Joki, T
    Abe, T
    Ohno, T
    JOURNAL OF IMMUNOTHERAPY, 1999, 22 (03): : 245 - 250
  • [3] Bioactive murine and human interleukin-12 fusion proteins which retain antitumor activity in vivo
    Lieschke, GJ
    Rao, PK
    Gately, MK
    Mulligan, RC
    NATURE BIOTECHNOLOGY, 1997, 15 (01) : 35 - 40
  • [4] Antitumor effects of the combination immunotherapy with interleukin-12 and tumor necrosis factor alpha in mice
    Lasek, W
    Feleszko, W
    Golab, J
    Stoklosa, T
    Marczak, M
    Dabrowska, A
    Malejczyk, M
    Jakobisiak, M
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 1997, 45 (02) : 100 - 108
  • [5] Antitumor effects of the combination immunotherapy with interleukin-12 and tumor necrosis factor α in mice
    W. Lasek
    Wojciech Feleszko
    Jakub Goląb
    Tomasz Stokłosa
    Maria Marczak
    Anna Dąbrowska
    Magdalena Malejczyk
    Marek Jakóbisiak
    Cancer Immunology, Immunotherapy, 1997, 45 : 100 - 108
  • [6] In vivo gene therapy with interleukin-12 inhibits primary vascular tumor growth and induces apoptosis in a mouse model
    Wang, C
    Quevedo, ME
    Lannutti, BJ
    Gordon, KB
    Guo, DQ
    Sun, W
    Paller, AS
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1999, 112 (05) : 775 - 781
  • [7] In vivo therapeutic effects of interleukin-12 against highly metastatic residual lymphoma
    Verbik, DJ
    Stinson, WW
    Brunda, MJ
    Kessinger, A
    Joshi, SS
    CLINICAL & EXPERIMENTAL METASTASIS, 1996, 14 (03) : 219 - 229
  • [8] Interleukin-12 inhibits angiogenesis induced by human tumor cell lines in vivo
    Majewski, S
    Marczak, M
    Szmurlo, A
    Jablonska, S
    Bollag, W
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1996, 106 (05) : 1114 - 1118
  • [9] Role of chitosan co-formulation in enhancing interleukin-12 delivery and antitumor activity
    Yang, Lirong
    Zaharoff, David A.
    BIOMATERIALS, 2013, 34 (15) : 3828 - 3836
  • [10] Intravesical chitosan/interleukin-12 immunotherapy induces tumor-specific systemic immunity against murine bladder cancer
    Sean G. Smith
    Bhanu prasanth Koppolu
    Sruthi Ravindranathan
    Samantha L. Kurtz
    Lirong Yang
    Matthew D. Katz
    David A. Zaharoff
    Cancer Immunology, Immunotherapy, 2015, 64 : 689 - 696