THE MEMBRANE HYPOTHESIS OF SCHIZOPHRENIA

被引：289
作者：
HORROBIN, DF
GLEN, AIM
VADDADI, K
机构：
[1] CRAIG DUNAIN HOSP,HIGHLAND PSYCHIAT RES GRP,INVERNESS,SCOTLAND
[2] MAROONDAH HOSP,MELBOURNE,VIC,AUSTRALIA
来源：
SCHIZOPHRENIA RESEARCH | 1994年 / 13卷 / 03期
关键词：
PHOSPHOLIPID METABOLISM; CELL MEMBRANE; HYPOTHESIS; (SCHIZOPHRENIA);
D O I：
10.1016/0920-9964(94)90043-4
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
The phospholipid structure of neuronal membranes is essential for, normal functioning of the nervous system. Evidence is accumulating that phospholipid metabolism in both brain and red blood cells may be disturbed in schizophrenia. In particular, in patients with negative symptoms, levels of arachidonic acid and docosahexanoic acid in red blood cell membrane phospholipids are severely abnormal. The membrane hypothesis of schizophrenia may represent a new and fruitful paradigm for future research.
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收藏
页码：195 / 207
页数：13
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