VISUALIZATION OF POLYMERCURIMETHANE-LABELED BACTERIOPHAGE-FD IN THE SCANNING-TRANSMISSION ELECTRON-MICROSCOPE

被引：19

作者：

LIPKA, JJ ^{[1
]}

LIPPARD, SJ ^{[1
]}

WALL, JS ^{[1
]}

机构：

[1] BROOKHAVEN NATL LAB,DEPT BIOL,UPTON,NY 11973

来源：

SCIENCE | 1979年 / 206卷 / 4425期

关键词：

D O I：

10.1126/science.92053

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Each of the 2700 coat proteins of fd bacteriophage was labeled with tetrakis(acetoxymercuri)methane (TAMM) or aquoglycylmethionineplatinum(II). The TAMM-labeled specimens reveal striking bright spots in the scanning transmission electron microscope which arise from clustering. Measurements of mass show increases consistent with the addition of four mercury atoms or one platinum atom, respectively, to each coat protein.

引用

页码：1419 / 1421

页数：3

共 13 条

[1]

Day Lucien., COMMUNICATION

[2]

HUICHI S, 1970, B CHEM SOC JPN, V43, P3849

[3] INTRODUCTION OF SULFHYDRYL GROUPS INTO PROTEINS USING ACETYLMERCAPTOSUCCINIC ANHYDRIDE [J].