Portal Vein Thrombosis in a Chirrotic Patient with Immune Thrombocytopenic Purpura During Eltrombopag Treatment

被引:0
作者
Ilhan, Gul [1 ]
Acipayam, Can [2 ]
机构
[1] Hatay Antakya Devlet Hastanesi, Hematol Bolumu, TR-31100 Antakya, Turkey
[2] Mustafa Kemal Univ, Tip Fak, Pediat Hematol & Onkol Bolumu, Antakya, Turkey
关键词
Portal Vein; Thrombosis; Immune; Thrombocytopenia; Eltrombopag;
D O I
10.4328/JCAM.2540
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Portal vein thrombosis (PVT) is a rare but serious complication in liver cirrhosis. Eltrombopag is a new, second generation agent used for immune thrombocytopenic purpura (ITP). It may cause thrombotic events. PVT has been rarely reported as a life threatening complication in some cirrhotic patients during eltrombopag using. We presented 63 years old cirrhotic and immune thrombocytopenic patient who had PVT after eltrombopag.
引用
收藏
页码:35 / 37
页数:3
相关论文
共 8 条
[1]   Eltrombopag before Procedures in Patients with Cirrhosis and Thrombocytopenia [J].
Afdhal, Nezam H. ;
Giannini, Edoardo G. ;
Tayyab, Ghias ;
Mohsin, Aftab ;
Lee, Jin-Woo ;
Andriulli, Angelo ;
Jeffers, Lennox ;
McHutchison, John ;
Chen, Pei-Jer ;
Han, Kwang-Hyub ;
Campbell, Fiona ;
Hyde, Denise ;
Brainsky, Andres ;
Theodore, Dickens .
NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (08) :716-724
[2]   Portal vein thrombosis as complication of romiplostim treatment in a cirrhotic patient with hepatitis C-associated immune thrombocytopenic purpura [J].
Dultz, Georg ;
Kronenberger, Bernd ;
Azizi, Alireza ;
Mihm, Ulrike ;
Vogl, Thomas J. ;
Sarrazin, Ulrike ;
Sarrazin, Christoph ;
Zeuzem, Stefan ;
Hofmann, Wolf-Peter .
JOURNAL OF HEPATOLOGY, 2011, 55 (01) :229-232
[3]  
Kawano N, 2013, J CLIN EXP HEMATOP, V53, P151
[4]   Portal vein thrombosis in liver cirrhosis [J].
Kinjo, Nao ;
Kawanaka, Hirofumi ;
Akahoshi, Tomohiko ;
Matsumoto, Yoshihiro ;
Kamori, Masahiro ;
Nagao, Yoshihiro ;
Hashimoto, Naotaka ;
Uehara, Hideo ;
Tomikawa, Morimasa ;
Shirabe, Ken ;
Maehara, Yoshihiko .
WORLD JOURNAL OF HEPATOLOGY, 2014, 6 (02) :64-71
[5]  
Komori A, 2011, PHASE 2 TRIAL ELTROM, V52, p147A
[6]   Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C [J].
McHutchison, John G. ;
Dusheiko, Geoffrey ;
Shiffman, Mitchell L. ;
Rodriguez-Torres, Maribel ;
Sigal, Samuel ;
Bourliere, Marc ;
Berg, Thomas ;
Gordon, Stuart C. ;
Campbell, Fiona M. ;
Theodore, Dickens ;
Blackman, Nicole ;
Jenkins, Julian ;
Afdhal, Nezam H. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (22) :2227-2236
[7]   Thrombocytopenia associated with hepatitis C viral infection [J].
Nagamine, T ;
Ohtuka, T ;
Takehara, K ;
Arai, T ;
Takagi, H ;
Mori, M .
JOURNAL OF HEPATOLOGY, 1996, 24 (02) :135-140
[8]   International consensus report on the investigation and management of primary immune thrombocytopenia [J].
Provan, Drew ;
Stasi, Roberto ;
Newland, Adrian C. ;
Blanchette, Victor S. ;
Bolton-Maggs, Paula ;
Bussel, James B. ;
Chong, Beng H. ;
Cines, Douglas B. ;
Gernsheimer, Terry B. ;
Godeau, Bertrand ;
Grainger, John ;
Greer, Ian ;
Hunt, Beverley J. ;
Imbach, Paul A. ;
Lyons, Gordon ;
McMillan, Robert ;
Rodeghiero, Francesco ;
Sanz, Miguel A. ;
Tarantino, Michael ;
Watson, Shirley ;
Young, Joan ;
Kuter, David J. .
BLOOD, 2010, 115 (02) :168-186