ESTRADIOL BINDING IN THE SEXUALLY DIMORPHIC NUCLEUS OF THE PREOPTIC ANTERIOR HYPOTHALAMIC AREA OF ADULT MALE FERRETS AND IN THE EQUIVALENT REGION OF FEMALES
A large number of estradiol-concentrating cells were visualized by autoradiography in a subpopulation of large neurons located in and around the sexually dimorphic male nucleus of the preoptic/anterior hypothalamic area (MN-POA/AH) of castrated male ferrets and in a comparable dorsal portion of the POA/AH of ovariectomized females. Considerably fewer estradiol-labelled cells were seen in the non-dimorphic ventral POA/AH nucleus of both sexes. Estrogen binding in cells in or around the MN-POA/AH may contribute to the formation of this sexually dimorphic nucleus in fetal males and may mediate specific estrogen-dependent behavioral functions in adulthood.
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UNIV CALIF LOS ANGELES, BRAIN RES INST, DEPT ANAT & CELL BIOL, NEUROENDOCRINOL LAB, LOS ANGELES, CA 90024 USAUNIV CALIF LOS ANGELES, BRAIN RES INST, DEPT ANAT & CELL BIOL, NEUROENDOCRINOL LAB, LOS ANGELES, CA 90024 USA
RHEES, RW
SHRYNE, JE
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UNIV CALIF LOS ANGELES, BRAIN RES INST, DEPT ANAT & CELL BIOL, NEUROENDOCRINOL LAB, LOS ANGELES, CA 90024 USAUNIV CALIF LOS ANGELES, BRAIN RES INST, DEPT ANAT & CELL BIOL, NEUROENDOCRINOL LAB, LOS ANGELES, CA 90024 USA
SHRYNE, JE
GORSKI, RA
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UNIV CALIF LOS ANGELES, BRAIN RES INST, DEPT ANAT & CELL BIOL, NEUROENDOCRINOL LAB, LOS ANGELES, CA 90024 USAUNIV CALIF LOS ANGELES, BRAIN RES INST, DEPT ANAT & CELL BIOL, NEUROENDOCRINOL LAB, LOS ANGELES, CA 90024 USA
机构:
Univ Massachusetts, Ctr Neuroendocrine Studies, Amherst, MA 01003 USAUniv Massachusetts, Dept Vet & Anim Sci, Amherst, MA 01003 USA
Intlekofer, K. A.
Petersen, S. L.
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Univ Massachusetts, Dept Vet & Anim Sci, Amherst, MA 01003 USA
Univ Massachusetts, Ctr Neuroendocrine Studies, Amherst, MA 01003 USAUniv Massachusetts, Dept Vet & Anim Sci, Amherst, MA 01003 USA