ESTRADIOL BINDING IN THE SEXUALLY DIMORPHIC NUCLEUS OF THE PREOPTIC ANTERIOR HYPOTHALAMIC AREA OF ADULT MALE FERRETS AND IN THE EQUIVALENT REGION OF FEMALES

被引：12
|
作者：
TOBET, SA
BAUM, MJ
机构：
[1] HARVARD UNIV,SCH MED,PROGRAM NEUROSCI,BOSTON,MA 02115
[2] BOSTON UNIV,DEPT BIOL,BOSTON,MA 02215
来源：
BRAIN RESEARCH | 1991年 / 546卷 / 02期
关键词：
ESTROGEN RECEPTOR; SEXUALLY DIMORPHIC NUCLEUS; FERRET; STEROID AUTORADIOGRAPHY;
D O I：
10.1016/0006-8993(91)91500-Z
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A large number of estradiol-concentrating cells were visualized by autoradiography in a subpopulation of large neurons located in and around the sexually dimorphic male nucleus of the preoptic/anterior hypothalamic area (MN-POA/AH) of castrated male ferrets and in a comparable dorsal portion of the POA/AH of ovariectomized females. Considerably fewer estradiol-labelled cells were seen in the non-dimorphic ventral POA/AH nucleus of both sexes. Estrogen binding in cells in or around the MN-POA/AH may contribute to the formation of this sexually dimorphic nucleus in fetal males and may mediate specific estrogen-dependent behavioral functions in adulthood.
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页码：345 / 350
页数：6
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