SYNTHESIS OF NITROGEN-OXIDES FROM L-ARGININE BY MACROPHAGE CYTOSOL - REQUIREMENT FOR INDUCIBLE AND CONSTITUTIVE COMPONENTS

被引：137

作者：

STUEHR, DJ ^{[1
]}

KWON, NS ^{[1
]}

GROSS, SS ^{[1
]}

THIEL, BA ^{[1
]}

LEVI, R ^{[1
]}

NATHAN, CF ^{[1
]}

机构：

[1] CORNELL UNIV, MED CTR, COLL MED, DEPT PHARMACOL, NEW YORK, NY 10021 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1989年 / 161卷 / 02期

关键词：

D O I：

10.1016/0006-291X(89)92615-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：420 / 426

页数：7

共 17 条

[1] AN L-ARGININE-DEPENDENT MECHANISM MEDIATES KUPFFER CELL-INHIBITION OF HEPATOCYTE PROTEIN-SYNTHESIS INVITRO [J].

BILLIAR, TR ;

CURRAN, RD ;

STUEHR, DJ ;

WEST, MA ;

BENTZ, BG ;

SIMMONS, RL .

JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 169 (04) :1467-1472

[2]

DING AH, 1988, J IMMUNOL, V141, P2407

[3] NITRATE BIOSYNTHESIS IN MAN [J].

GREEN, LC ;

DELUZURIAGA, KR ;

WAGNER, DA ;

RAND, W ;

ISTFAN, N ;

YOUNG, VR ;

TANNENBAUM, SR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (12) :7764-7768

[4] MACROPHAGE CYTOTOXICITY - ROLE FOR L-ARGININE DEIMINASE AND IMINO-NITROGEN OXIDATION TO NITRITE [J].

HIBBS, JB ;

TAINTOR, RR ;

VAVRIN, Z .

SCIENCE, 1987, 235 (4787) :473-476

[5] NITRIC-OXIDE - A CYTO-TOXIC ACTIVATED MACROPHAGE EFFECTOR MOLECULE [J].

HIBBS, JB ;

TAINTOR, RR ;

VAVRIN, Z ;

RACHLIN, EM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 157 (01) :87-94

[6] ENDOTHELIUM-DERIVED RELAXING FACTOR PRODUCED AND RELEASED FROM ARTERY AND VEIN IS NITRIC-OXIDE [J].

IGNARRO, LJ ;

BUGA, GM ;

WOOD, KS ;

BYRNS, RE ;

CHAUDHURI, G .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (24) :9265-9269

[7] MACROPHAGE SYNTHESIS OF NITRITE, NITRATE, AND N-NITROSAMINES - PRECURSORS AND ROLE OF THE RESPIRATORY BURST [J].

IYENGAR, R ;

STUEHR, DJ ;

MARLETTA, MA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (18) :6369-6373

[8] MACROPHAGE OXIDATION OF L-ARGININE TO NITRITE AND NITRATE - NITRIC-OXIDE IS AN INTERMEDIATE [J].

MARLETTA, MA ;

YOON, PS ;

IYENGAR, R ;

LEAF, CD ;

WISHNOK, JS .

BIOCHEMISTRY, 1988, 27 (24) :8706-8711

[9]

NAKAGAWARA A, 1983, J IMMUNOL METHODS, V56, P261

[10] VASCULAR ENDOTHELIAL-CELLS SYNTHESIZE NITRIC-OXIDE FROM L-ARGININE [J].

PALMER, RMJ ;

ASHTON, DS ;

MONCADA, S .

NATURE, 1988, 333 (6174) :664-666

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