IMIDAZO[1',2'(3,4)]PYRIMIDO[6,1-A]ISOQUINOLINE AND PYRIMIDO[1',2'(3,4)]PYRIMIDO[6,1-A]ISOQUINOLINE RING-SYSTEMS BY TANDEM CYCLIZATION

被引：0
作者：
FULOP, F
WAMHOFF, H
SOHAR, P
机构：
[1] UNIV BONN, INST ORGAN CHEM & BIOCHEM, D-53121 BONN, GERMANY
[2] EOTVOS LORAND UNIV, DEPT GEN & INORGAN CHEM, H-1518 BUDAPEST, HUNGARY
来源：
SYNTHESIS-STUTTGART | 1995年 / 07期
关键词：
2-CHLORALKYL ISOCYANATES; IMIDAZO[1',2'3,4]PYRIMIDO[6,1-A]ISOQUINOLINE; PYRIMIDO[1',2'3,4]PYRIMIDO[6,1-A]ISOQUINOLINE; NEW RING SYSTEMS; TANDEM CYCLIZATION;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reactions of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinoline-1-acetonitriles 3 and 4 with 2-chloroethyl and 3-chloropropyl isocyanates resulted in ureas 5-8, which were transformed with sodium methylate into the new ring systems 9,10-dimethoxy- and 9,10-diethoxy-5H-2,3,7,8,12b,13-hexahydroimidazo[1',2':3,4]pyrimido[6,1-a]isoquinolin-5-one (9,10) and 11,12-dimethoxy- and 11,12-diethoxy-2H,6H-3,4,8,9,13b,14-hexahydropyrimido[1',2':3,4]pyrimido[6,1-a]isoquinolin-6-one (11, 12) by tandem cyclization.
引用
收藏
页码：863 / 867
页数：5
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