SIMULTANEOUS HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF FURAZOLIDONE AND NIFUROXIME IN DOSAGE FORMS

被引：5

作者：

HASSAN, SM

IBRAHIM, FA

HEFNAWY, MM

机构：

[1] Analytical Chemistry Department, Faculty of Pharmacy, University of Mansoura, Mansoura

来源：

ANALYTICAL LETTERS | 1990年 / 23卷 / 04期

关键词：

dosage forms; Furazolidone; HPLC; Nifuroxime;

D O I：

10.1080/00032719008052467

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A reversed-phase high-performance liquid chromatographic method for the simultaneous determination of furazolidone and ifuroxime in vaginal suppositories is described. A lichrosorb R.P. 18 (4 x 250 mm) 5 column μm and a mobile phase consisting of methanol-water-buffer pH 3 (40:55:5) were used. Calibration graphs were rectilinear over the concentration range 1–10 μg/ml [or both drugs. Separation was achieved in 12 min. at a wavelength of 350 nm. The proposed method was applied to suppositories containing. the two species, and the results obtained were accurate and precise. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：599 / 606

页数：8

共 7 条

[1] QUANTITATIVE DETERMINATION OF FURAZOLIDONE AND NIFUROXIME IN A WATER-SOLUBLE SUPPOSITORY BASE [J].