SINGLE INJECTION TECHNIQUE FOR SUBTRACTION OF BLOOD BACKGROUND IN HIPPURAN-I-131 RENOGRAMS

A method of subtracting blood background during probe-renography is presented which does not require prior injection of RIHSA and which produces results approximately 11% higher than the RIHSA method. The new method treats the renogram up to two-and-a-half minutes as a combination of a fraction of the blood curve and a fraction of the integral of the blood curve. Analysis of the data, using either a computer or a programmed calculator, enables these two fractions to be calculated, hence producing the 'background subtraction factor' and the 'uptake constant'.