REACTION OF DIHYDROCODEINE TARTRATE WITH BROMINE IN ACETIC-ACID SOLUTION

被引：0

作者：

GORLITZER, K

SCHUMANN, R

机构：

[1] TECH UNIV CAROLO WILHELMINA BRAUNSCHWEIG,INST PHARMAZEUT CHEM,W-3300 BRAUNSCHWEIG,GERMANY

[2] FREE UNIV BERLIN,INST PHARMAZIE,W-1000 BERLIN 33,GERMANY

来源：

PHARMAZIE | 1993年 / 48卷 / 07期

关键词：

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Dependent on the reaction conditions dihydrocodeine is brominated to give the 1-bromo and 1,2-dibromo derivatives 2-4. Irradiation by sunlight at the same time yields the 1-bromo-10alpha-hydroxy compounds 5 and 6.

引用

页码：525 / 527

页数：3

共 9 条

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[4] HYDROXY-MORPHINANE .10. UBER EIN PHOTOOXYDATIONSPRODUKT VON (+)-3-METHOXY-N-METHYL-MORPHINAN
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[J]. HELVETICA CHIMICA ACTA, 1956, 39 (07) : 2053 - 2062
[5] THE STEREOCHEMISTRY OF 10-HYDROXYCODEINE DERIVATIVES
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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1955, 77 (16) : 4330 - 4335
[6] Demonstration of monobromide- and monochloride-codeine and their behaviour in catalytic reduction
Speyer, E
Rosenfeld, H
[J]. BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT, 1925, 58 : 1110 - 1113
[7] Speyer E, 1923, LIEBIGS ANN CHEM, V432, P233
[8] ZYKA J, 1954, Pharmazie, V9, P812
[9] 1978, EUROPAISCHES ARZNEIB, V3, P160

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