Prospective, randomized trials conducted over the past 10 years have changed the management of patients with advanced cervical cancer. Overall and progression-free survivals were superior for patients receiving cisplatin-based combination radiochemotherapy than that of radiotherapy. Lymph node status needs to be evaluated before treatment by laparoscopy. Paraaortic radiotherapy should be performed only in patients with positive paraaortic lymph nodes. Higher rate of reversible hematologic and gastrointestinal toxicity effects in the combined-therapy group.