ENDOSCOPIC INJECTION SCLEROTHERAPY IN NONVARICEAL UPPER GASTROINTESTINAL-BLEEDING - A COMPARATIVE-STUDY OF POLIDOCANOL AND THROMBIN

被引：20

作者：

BENEDETTI, G

SABLICH, R

LACCHIN, T

机构：

[1] Gastrointestinal Unit, Department of Surgery II, General Hospital, Pordenone

来源：

SURGICAL ENDOSCOPY-ULTRASOUND AND INTERVENTIONAL TECHNIQUES | 1991年 / 5卷 / 01期

关键词：

GASTROINTESTINAL BLEEDING; ENDOSCOPY; INJECTION SCLEROTHERAPY;

D O I：

10.1007/BF00591383

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

To date several agents have been used to achieve haemostasis in patients with non-variceal upper gastrointestinal bleeding using endoscopic sclerotherapy techniques. Polidocanol has been widely used but local complications have been reported after treatment. We have compared the efficacy and safety of thrombin and polidocanol in 82 consecutive patients with ongoing or recent bleeding from duodenal, gastric, or anastomotic ulcers. Primary control of haemostasis from spurting vessels was achieved in 90% of cases using polidocanol and in 86.6% using thrombin. Definitive haemostasis was obtained in 80% of patients in both groups. When a non-bleeding vessel was visible, injection of polidocanol or thrombin effectively prevented rebleeding in 90.9% and 85.7% of cases, respectively. When a non-bleeding sentinel clot was present, injection of polidocanol or thrombin provided definitive haemostasis in 100% and 92.8% of cases, respectively. No statistically significant difference was evident between the two agents. In the polidocanol group, one local haemorrhagic complication was noted. No general or local complications were recorded in the thrombin group.

引用

页码：28 / 30

页数：3

共 12 条

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