2 NEW BIOACTIVE CYCLIC PEROXIDES FROM THE MARINE SPONGE PLAKORTIS-ANGULOSPICULATUS

被引:54
作者
GUNASEKERA, SP
GUNASEKERA, M
GUNAWARDANA, GP
MCCARTHY, P
BURRES, N
机构
[1] Division of Biomedical Marine Research, Harbor Branch Oceanographie Institution, Fort Pierce
来源
JOURNAL OF NATURAL PRODUCTS | 1990年 / 53卷 / 03期
关键词
D O I
10.1021/np50069a021
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Two new antifungal and cytotoxic cyclic-peroxide-containing acids, 1 and 3, were isolated from a marine sponge, Plakortis angulospiculatus, which was collected by scuba off the coast of Venezuela. The structures were elucidated through spectral and chemical analysis of the corresponding methyl esters, 2 and 4. The acids are potent cytoxic and antifungal agents although their esters are only cytotoxic. © 1990, American Chemical Society. All rights reserved.
引用
收藏
页码:669 / 674
页数:6
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