STUDY TO KNOW THE INCIDENCE OF INSULIN RESISTANCE IN POLYCYSTIC OVARIAN SYNDROME PATIENTS

Objective: To determine the incidence of insulin resistance (IR) in polycystic ovarian syndrome patients with simple insulin resistance indices and to know the relation of PCOS clinical manifestations with insulin resistance indices. Study Design: A cross-sectional study. Place and Duration: In the Endocrinology Department of Services hospital, From December 2016 to December 2017 for duration of one year. Methodology:. A hundred patients who met the Rotterdam 2003 diagnostic criteria for polycystic ovarian syndrome were selected for the study. Descriptive statistics was recorded with standard deviation and frequency. Using fasting insulin levels (> 10 IU / ml) Insulin resistance (IR) was calculated, fasting glucose /insulin ratio (> 4.6). The different indirect IR signals were calculated as McAuley (< 5.8), QUICKI (< 0.357) and HOMA-IR (> 2.7). Findings: HOMA-IR, QUICKI and McAuley values were 65%, 88% and 51.2% in patients with PCOS, respectively. Patients with Blood sugar fasting levels (> 10 uu / ml) were 76.02%. With hirsutism, infertility and obesity the most common presentation was Menstrual irregularities. There was a strong relation between various irregularities, insulin resistance and hyperinsulinemia. Conclusion: High-frequency insulin resistance and hyperinsulinemia were seen in patients with polycystic ovariansyndrome. With insulin resistance indices great numbers of clinical manifestations are related.