THE REACTIVE SERINE RESIDUE OF EPIDERMOLYTIC TOXIN-A

被引:23
作者
BAILEY, CJ
SMITH, TP
机构
[1] Department of Biochemistry, Trinity College
关键词
D O I
10.1042/bj2690535
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Comparison of amino acid sequence data suggested that there may be a functional relationship between the staphylococcal epidermolytic toxins and V8 proteinase. The hypothesis was tested by treating epidermolytic toxin with di-isopropyl phosphorofluoridate, which bound specifically at serine-195, the homologue of the active-site serine residue of V8 proteinase.
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页码:535 / 537
页数:3
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