Transcriptional regulation of the human telomerase reverse transcriptase New insights

被引：6
|
作者：
Chebel, Amel [1 ]
Ffrench, Martine [1 ,2 ]
机构：
[1] Univ Lyon 1, CNRS UMR 5239, ENS UCB HCL, Fac Lyon Sud, Oullins, France
[2] Hosp Civils Lyon, Lab Hematol, Pierre Benite, France
来源：
TRANSCRIPTION-AUSTIN | 2010年 / 1卷 / 01期
关键词：
hTERT; NFAT; cell stimulation; tumorigenesis; immunosuppression;
D O I：
10.4161/trns.1.1.12062
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
hTERT and NFAT were thought until recently to belong to separate metabolic compartments. The involvement of NFAT in the induction of hTERT transcription, suggested by hTERT expression variations during lymphocyte stimulation and immunosuppressive treatments, explains the link between hTERT expression and cell stimulation and offers new insights for therapeutic developments.
引用
收藏
页码：27 / 31
页数：5
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