ITRACONAZOLE FOR THE TREATMENT OF HISTOPLASMOSIS IN CATS

被引：48

作者：

HODGES, RD ^{[1
]}

LEGENDRE, AM ^{[1
]}

ADAMS, LG ^{[1
]}

WILLARD, MD ^{[1
]}

PITTS, RP ^{[1
]}

MONCE, K ^{[1
]}

NEEDELS, CC ^{[1
]}

WARD, H ^{[1
]}

机构：

[1] UNIV TENNESSEE,COLL VET MED,DEPT URBAN PRACTICE,KNOXVILLE,TN 37901

来源：

JOURNAL OF VETERINARY INTERNAL MEDICINE | 1994年 / 8卷 / 06期

关键词：

D O I：

10.1111/j.1939-1676.1994.tb03260.x

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Eight cats with histoplasmosis were treated with itraconazole at 5 mg/kg per dose PO bid, There were multiple sites of infection, and 2 of the cats had hypercalcemia that was attributed to the histoplasmosis, All 8 cats were eventually cured, but 2 cats experienced recurrences of disease after completion of therapy, requiring 2 to 3 additional months of itraconazole, There were no clinically relevant adverse effects during treatment. Although a limited number of cats were treated, the study suggests that itraconazole is a well-tolerated and effective drug for the treatment of histoplasmosis in the cat.

引用

页码：409 / 413

页数：5

共 39 条

[1]

Breitschwerdt EB, Halliwell WH, Burk RL, Et al., Feline histoplasmosis, J Am Anim Hosp Assoc, 13, pp. 216-222, (1977)

[2]

Wolf AM, Troy GC., Deep mycotic diseases, Textbook of Veterinary Internal Medicine: Diseases of the Dog and Cat, pp. 351-354, (1989)

[3]

Wolf AM, Belden MN., Feline histoplasmosis: A literature review and retrospective study of 20 new cases, J Am Anim Hosp Assoc, 20, pp. 995-998, (1984)

[4]

Wolf AM., Histoplasmosis, Infectious Diseases of the Dog and Cat, pp. 679-686, (1990)

[5]

Hermans PE., Antifungal agents used for deep‐seated mycotic infections, Mayo Clin Proc, 52, pp. 687-693, (1977)

[6]

Gwin RM, Makley TA, Wyman M., Et al., Multifocal ocular histoplasmosis in a dog and cat, J Am Vet Med Assoc, 176, pp. 638-642, (1980)

[7]

Mahaffey E., Gabbert N., Johnson D., Et al., Disseminated histoplasmosis in three cats, J Am Anim Hosp Assoc, 13, pp. 46-51, (1977)

[8]

Van Cutsen J., Van Gerven F., Janessen PAJ., Activity of orally, topically and parenterally administered itraconazole in the treatment of superficial and deep mycoses: Animal models, Clinical Infectious Diseases, 9, pp. 15-32, (1987)

[9]

Negroni R., Palmieri F., Karen IN, Et al., Oral treatment of paracoccidioidomycosis and histoplasmosis with itraconazole in humans, Rev Infect Dis, 9, pp. 47-50, (1987)

[10]

Pedersen NC., Fungal diseases, Feline Infectious Diseases, pp. 243-261, (1988)

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