AN EFFICIENT SYNTHESIS OF THE DOLABELLANES

被引：32

作者：

WILLIAMS, DR

COLEMAN, PJ

NEVILL, CR

ROBINSON, LA

机构：

[1] Department of Chemistry, Indiana University Bloomington

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 49期

关键词：

DOLABELLANE SYNTHESIS; INTRAMOLECULAR JULIA CONDENSATIONS;

D O I：

10.1016/S0040-4039(00)61504-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Eleven-membered carbocycles have been prepared by the intramolecular condensations of alpha-sulfonyl carbanions with alpha,beta-unsaturated aldehydes. Desulfonylation provides an efficient stereocontrolled synthesis of allylic alcohols featuring the [9.3.0] cyclotetradecane skeleton which characterizes the dolabellane diterpenes.

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页码：7895 / 7898

页数：4

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