DEMONSTRATION OF CIRCULATING PNEUMOCOCCAL IMMUNOGLOBULIN-G IMMUNE-COMPLEXES IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA BY MEANS OF AN ENZYME-LINKED-IMMUNOSORBENT-ASSAY

被引：31
作者：
HOLLOWAY, Y [1 ]
SNIJDER, JAM [1 ]
BOERSMA, WG [1 ]
机构：
[1] UNIV GRONINGEN HOSP,DEPT PULM DIS,9700 RB GRONINGEN,NETHERLANDS
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 1993年 / 31卷 / 12期
关键词：
D O I：
10.1128/JCM.31.12.3247-3254.1993
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
An enzyme-linked immunosorbent assay was developed for quantitation of circulating immune complexes (CICs) containing specific antipneumococcal immunoglobulin G (IgG). These CICs were detected in 17 (85%) of 20 patients with bacteremic pneumococcal pneumonia, 4 (36.4%) of 11 patients with probable pneumococcal pneumonia, 3 (16.7%) of 18 patients with pneumonia of other (nonpneumococcal) etiology, and 13 (41.9%) of 31 patients with pneumonia of unknown etiology. There was no correlation between CICs and serum IgG antibody levels. Pneumococcal capsular antigen was demonstrated in dissociated CICs by latex agglutination.
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页码：3247 / 3254
页数：8
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