ANTIMICROBIAL ACTIVITY OF COPPER(II) COMPLEXES

被引：0

作者：

Congradyova, Andrea ^{[1
]}

Jomova, Klaudia ^{[1
]}

Kuckova, Lenka ^{[2
]}

Kozisek, Jozef ^{[2
]}

Moncol, Jan ^{[2
]}

Valko, Marian ^{[2
]}

机构：

[1] Constantine Philosopher Univ, Dept Chem, Fac Nat Sci, Tr A Hlinku 1, Nitra 94974, Slovakia

[2] Slovak Tech Univ, Dept Phys Chem, Fac Chem & Food Technol, Bratislava 81237, Slovakia

来源：

JOURNAL OF MICROBIOLOGY BIOTECHNOLOGY AND FOOD SCIENCES | 2014年 / 3卷

关键词：

5-chlorosalicylic acid; antimicrobial activity; copper complex; 1,10-phenanthroline; neocuproine;

D O I：

暂无

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Two novel copper(II) 5-chlorosalicylate complexes with either 1,10-phenantroline or its methyl derivative 2,9-dimethyl-1,10-phenanthroline (neocuproine) have been prepared and studied. A potential antimicrobial or antifungal activity of both complexes has been tested on prokaryotic Escherichia coli and eukaryotic Saccharomyces cerevisiae model organisms. Crystal structure of [Cu(phen)(5-Clsal)(5-ClsalH(2))](2) a dimeric structure, whereas the second complex of formula [Cu(H2O)(5-Clsal)(Neo)] has been shown to be monomeric. Our results confirmed the toxic effect of prepared copper complexes as well as bioactive ligands on the yeast and bacteria growth. The effect of copper complexes was stronger compared to the solutions of free ligands. Our preliminary results showed that the complex [Cu(H2O)(5-Clsal)(Neo)] exhibited higher antimicrobial activity compared to the complex [Cu(phen)(5-Clsal)(5-ClsalH(2))](2).

引用

页码：67 / 70

页数：4

共 50 条

[1] Syntheses, Crystal Structures and Antimicrobial Activity of Copper(II) and Zinc(II) Complexes with Aroylhydrazones
Hai Shi-Kun
Lou Shu-Fang
Qiu Xiao-Yang
CHINESE JOURNAL OF INORGANIC CHEMISTRY, 2016, 32 (05) : 906 - 912
[2] Synthesis, antiproliferative activity and mechanism of copper(II)-thiosemicarbazone complexes as potential anticancer and antimicrobial agents
Qi, Jinxu
Wang, Xuejiao
Liu, Taichen
Kandawa-Schulz, Martha
Wang, Yihong
Zheng, Xinhua
JOURNAL OF COORDINATION CHEMISTRY, 2020, 73 (07) : 1208 - 1221
[3] SYNTHESIS, STEREOCHEMISTRY AND ANTIMICROBIAL ACTIVITY OF COPPER(II) AND NICKEL(II) COMPLEXES OF 4-PHENYLSEMICARBAZONES
Nfor, Emmanuel N.
Esemu, Seraphine N.
Ayimele, Godfred A.
Eno, Ededet A.
Iniama, Grace E.
Offiong, E. Offiong
BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA, 2011, 25 (03) : 361 - 370
[4] Synthesis, Crystal Structures and Antimicrobial Activity of Dinuclear Copper(II) Complexes with bis-Schiff Bases
Qiu Xiao-Yang
CHINESE JOURNAL OF INORGANIC CHEMISTRY, 2014, 30 (07) : 1667 - 1672
[5] Recent Studies on the Antimicrobial Activity of Copper Complexes
O. A. Zalevskaya
Y. A. Gur’eva
Russian Journal of Coordination Chemistry, 2021, 47 : 861 - 880
[6] Recent Studies on the Antimicrobial Activity of Copper Complexes
Zalevskaya, O. A.
Gur'eva, Y. A.
RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, 2021, 47 (12) : 861 - 880
[7] Interaction of a copper(II)-Schiff base complexes with calf thymus DNA and their antimicrobial activity
Sabolova, D.
Kozurkova, M.
Plichta, T.
Ondrusova, Z.
Hudecova, D.
Simkovic, M.
Paulikova, H.
Valent, A.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2011, 48 (02) : 319 - 325
[8] Synthesis, characterization and antimicrobial activity of 5-(arylazo)salicylaldimines and their copper(II) complexes
Abbas, Samir Y.
Basyouni, Wahid M.
El-Bayouki, Khairy A. M.
APPLIED ORGANOMETALLIC CHEMISTRY, 2018, 32 (02)
[9] Copper(II) salicylideneglycinate complexes as potential antimicrobial agents
Valent, A
Melník, M
Hudecová, D
Dudová, B
Kivekäs, R
Sundberg, MR
INORGANICA CHIMICA ACTA, 2002, 340 : 15 - 20
[10] Synthesis, spectral characterization, and antimicrobial activity of copper(II), cobalt(II), and nickel(II) complexes of 3-formylchromoniminopropylsilatrane
Tharmaraj, P.
Kodimunthiri, D.
Sheela, C. D.
Priya, C. S. Shanmuga
JOURNAL OF COORDINATION CHEMISTRY, 2009, 62 (13) : 2220 - 2228

← 1 2 3 4 5 →