CARDIAC SODIUM-CALCIUM EXCHANGE RESEARCH NEW DIRECTIONS

被引:21
|
作者
PHILIPSON, KD
机构
关键词
D O I
10.1016/1050-1738(92)90038-T
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The sarcolemmal Na+-Ca2+ exchanger is the dominant myocardial Ca2+ efflux mechanism and has a central role in the regulation of contractility. Physiologic and molecular advances in Na+-Ca2+ exchange research have led a resurgence of interest in this system. Molecular cloning of the exchanger has recently been accomplished, and information on the molecular structure and reaction mechanism is forthcoming.
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页码:12 / 14
页数:3
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