AMINO-ACID ZWITTERION EQUILIBRIA .2. VIBRATIONAL AND NMR-STUDIES OF SUBSTITUTED THIAZOLIDINE-4-CARBOXYLIC ACIDS

被引：9

作者：

HOWARDLOCK, HE ^{[1
]}

LOCK, CJL ^{[1
]}

MARTINS, ML ^{[1
]}

机构：

[1] MCMASTER UNIV,DEPT PATHOL,INORGAN MED LAB,HAMILTON L8S 4M1,ONTARIO,CANADA

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1991年 / 69卷 / 11期

关键词：

AMINO ACID ZWITTERION EQUILIBRIA; THIAZOLIDINE CARBOXYLIC ACIDS;

D O I：

10.1139/v91-252

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Infrared and Raman spectra (4000-100 cm) of solid samples of seven different 2-phenyl-, N-benzoyl-, and 2-ethyl-2 methyl derivatives of L-cysteine and D-penicillamine have been observed and assigned. Proton and C-13 nuclear magnetic resonance spectra for the compounds have also been measured. Amino acid/zwitterion equilibria are discussed with reference to pK values and the vibrational spectra.

引用

页码：1721 / 1727

页数：7

共 8 条

[1] CLARKE HT, 1949, CHEM PENICILLIN, P962
[2] Colthup N. B., 1964, INTRO INFRARED RAMAN
[3] 2R,4S-2-(2'-METHYL-3'-HYDROXY-5'-HYDROXYMETHYLENEPYRIDINE-C4')-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID, THE PRODUCT OF THE REACTION OF D-PENICILLAMINE AND VITAMIN-B6
FAGGIANI, R
HOWARDLOCK, HE
LOCK, CJL
ORGIAS, R
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1991, 69 (01): : 1 - 7
[4] Hamilton W. C., 1968, HYDROGEN BONDING SOL
[5] D-PENICILLAMINE - CHEMISTRY AND CLINICAL USE IN RHEUMATIC DISEASE
HOWARDLOCK, HE
LOCK, CJL
MEWA, A
KEAN, WF
[J]. SEMINARS IN ARTHRITIS AND RHEUMATISM, 1986, 15 (04) : 261 - 281
[6] AMINO-ACID ZWITTERION EQUILIBRIA - VIBRATIONAL AND NUCLEAR-MAGNETIC-RESONANCE STUDIES OF METHYL-SUBSTITUTED THIAZOLIDINE-4-CARBOXYLIC ACIDS
HOWARDLOCK, HE
LOCK, CJL
MARTINS, ML
SMALLEY, PS
BELL, RA
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1986, 64 (06): : 1215 - 1219
[7] (S)-2,2,5,5-TETRAMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID - A COMPOUND WHICH EXISTS IN THE AMINO-ACID RATHER THAN THE ZWITTERION FORM
HOWARDLOCK, HE
LOCK, CJL
SMALLEY, PS
[J]. CANADIAN JOURNAL OF CHEMISTRY, 1985, 63 (09) : 2411 - 2419
[8] RIEMSCHNEIDER R, 1962, NATURFORSCHER, V176, P765

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