BINDING OF FORMYLMETHIONYL-TRNA AND AMINOACYL-TRNA TO RIBOSOMES

被引：23
作者：
OHTA, T
THACH, RE
机构：
[1] Department of Chemistry, Harvard University, Cambridge, MA
来源：
NATURE | 1968年 / 219卷 / 5151期
关键词：
D O I：
10.1038/219238a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Inhibition of aminoacyl-tRNA binding by the purified initiation factors f1 and f2 could be regarded as a mechanism for ensuring that only F-met-tRNA binds initially to the entry site, thereby preventing random or non-specific binding by aminoacyl-tRNA. This inhibition would be relieved by the hydrolysis of the GTP molecule normally involved in the binding of F-met-tRNA. © 1968 Nature Publishing Group.
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页码：238 / &
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