EFFECTS OF A PROTEIN PHOSPHATASE INHIBITOR, OKADAIC ACID, ON MEMBRANE CURRENTS OF ISOLATED GUINEA-PIG CARDIAC MYOCYTES

被引：261
作者：
HESCHELER, J
MIESKES, G
RUEGG, JC
TAKAI, A
TRAUTWEIN, W
机构：
[1] UNIV HEIDELBERG,INST PHYSIOL 2,NEUENHEIMER FELD 326,D-6900 HEIDELBERG 1,FED REP GER
[2] UNIV SAARLAND,INST PHYSIOL 2,D-6650 HOMBURG,FED REP GER
[3] UNIV GOTTINGEN,ZENTRUM INNERE MED,KLIN BIOCHEM ABT,D-3400 GOTTINGEN,FED REP GER
来源：
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY | 1988年 / 412卷 / 03期
关键词：
D O I：
10.1007/BF00582504
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
引用
收藏
页码：248 / 252
页数：5
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共 24 条
[11]   IMPROVED PATCH-CLAMP TECHNIQUES FOR HIGH-RESOLUTION CURRENT RECORDING FROM CELLS AND CELL-FREE MEMBRANE PATCHES [J].
HAMILL, OP ;
MARTY, A ;
NEHER, E ;
SAKMANN, B ;
SIGWORTH, FJ .
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1981, 391 (02) :85-100
[12]   REGULATION OF THE CARDIAC CALCIUM-CHANNEL BY PROTEIN PHOSPHATASES [J].
HESCHELER, J ;
KAMEYAMA, M ;
TRAUTWEIN, W ;
MIESKES, G ;
SOLING, HD .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1987, 165 (02) :261-266
[13]   SEPARATION AND CHARACTERIZATION OF 2 PHOSPHORYLASE PHOSPHATASE INHIBITORS FROM RABBIT SKELETAL-MUSCLE [J].
HUANG, FL ;
GLINSMANN, WH .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1976, 70 (02) :419-426
[14]   THE PROTEIN PHOSPHATASES INVOLVED IN CELLULAR-REGULATION .1. CLASSIFICATION AND SUBSTRATE SPECIFICITIES [J].
INGEBRITSEN, TS ;
COHEN, P .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1983, 132 (02) :255-261
[15]   ON THE MECHANISM OF BETA-ADRENERGIC REGULATION OF THE CA CHANNEL IN THE GUINEA-PIG HEART [J].
KAMEYAMA, M ;
HOFMANN, F ;
TRAUTWEIN, W .
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1985, 405 (03) :285-293
[16]   THE PROTEIN-SPECIFIC PHOSPHATASE-1 ANTAGONIZES THE BETA-ADRENERGIC INCREASE OF THE CARDIAC CA CURRENT [J].
KAMEYAMA, M ;
HESCHELER, J ;
MIESKES, G ;
TRAUTWEIN, W .
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1986, 407 (04) :461-463
[17]   ELECTROMECHANICAL EFFECTS OF OKADAIC ACID ISOLATED FROM BLACK SPONGE IN GUINEA-PIG VENTRICULAR MUSCLES [J].
KODAMA, I ;
KONDO, N ;
SHIBATA, S .
JOURNAL OF PHYSIOLOGY-LONDON, 1986, 378 :359-373
[18]   IDENTIFICATION OF 2 ISOENZYMES OF PROTEIN PHOSPHATASE-2C IN BOTH RABBIT SKELETAL-MUSCLE AND LIVER [J].
MCGOWAN, CH ;
COHEN, P .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1987, 166 (03) :713-722
[19]   CALCIUM-CHANNEL MODULATION BY NEUROTRANSMITTERS, ENZYMES AND DRUGS [J].
REUTER, H .
NATURE, 1983, 301 (5901) :569-574
[20]   OKADAIC ACID, A CYTO-TOXIC POLYETHER FROM 2 MARINE SPONGES OF THE GENUS HALICHONDRIA [J].
TACHIBANA, K ;
SCHEUER, PJ ;
TSUKITANI, Y ;
KIKUCHI, H ;
VANENGEN, D ;
CLARDY, J ;
GOPICHAND, Y ;
SCHMITZ, FJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (09) :2469-2471
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