STEREOSELECTIVE SYNTHESIS OF SYN-1,3-DIOLS

被引：11
|
作者：
MOHR, P
机构：
[1] Pharmaceutical Research Department, F. Hoffmann-La Roche Ltd
来源：
TETRAHEDRON LETTERS | 1991年 / 32卷 / 20期
关键词：
D O I：
10.1016/S0040-4039(00)79685-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
beta-Hydroxyalkynones 1, readily available from the corresponding beta-hydroxyesters, are reduced by DIBAL-H in THF at -78-degrees with good selectivity to syn-diols 2.
引用
收藏
页码：2219 / 2222
页数：4
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