STEREOSELECTIVE SYNTHESIS OF SYN-1,3-DIOLS

被引：11

作者：

MOHR, P

机构：

[1] Pharmaceutical Research Department, F. Hoffmann-La Roche Ltd

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 20期

关键词：

D O I：

10.1016/S0040-4039(00)79685-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

beta-Hydroxyalkynones 1, readily available from the corresponding beta-hydroxyesters, are reduced by DIBAL-H in THF at -78-degrees with good selectivity to syn-diols 2.

引用

页码：2219 / 2222

页数：4

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