Specific gene hypomethylation and cancer: New insights into coding region feature trends

被引：44

作者：

Daura-Oller, Elias ^{[1
]}

Cabre, Maria ^{[1
]}

Montero, Miguel A. ^{[1
]}

Paternain, Jose L. ^{[1
]}

Romeu, Antoni ^{[1
]}

机构：

[1] Rovira & Virgili Univ URV, Fac Chem, Biochem & Biotechnol Dept, C Marcelli Domingo S-N,Campus Sescelades, Tarragona 43007, Spain

来源：

BIOINFORMATION | 2009年 / 3卷 / 08期

关键词：

epigenetics; cancer; CpG islands; hypomethylation;

D O I：

10.6026/97320630003340

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.

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收藏

页码：340 / 343

页数：4

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