FREQUENCY OF THE F508-DELETION IN THE CFTR GENE IN TURKISH CYSTIC-FIBROSIS PATIENTS

被引：15

作者：

HUNDRIESER, J

BREMER, S

PEINEMANN, F

STUHRMANN, M

HOFFKNECHT, N

WULF, B

SCHMIDTKE, J

REISS, J

MAASS, G

TUMMLER, B

机构：

[1] MED HSCH HANOVER,BIOPHYS CHEM ABT,W-3000 HANOVER 61,GERMANY

[2] UNIV GOTTINGEN,INST HUMANGENET,W-3400 GOTTINGEN,GERMANY

[3] FREE UNIV BERLIN,INST HUMANGENET,W-1000 BERLIN 19,GERMANY

来源：

HUMAN GENETICS | 1990年 / 85卷 / 04期

关键词：

D O I：

10.1007/BF02428283

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The F508 deletion in the cystic fibrosis transmembrane conductance regulator (CFTR) gene was found in 8 out of 30 Turkish cystic fibrosis (CF) chromosomes (27%). Five Turkish ΔF508 CF chromosomes were associated with the risk haplotype B in KM19 (2 allele)/XV2c (1 allele). In the Turkish population, cystic fibrosis is predominantly caused by mutations other than the F508 deletion. © 1990 Springer-Verlag.

引用

页码：409 / 410

页数：2