TARGETS FOR THE ANTIVIRAL ACTIVITY OF PYRIMIDINE AND PURINE NUCLEOSIDE ANALOGS

被引：18
作者：
DECLERCQ, E
机构：
来源：
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 1987年 / 6卷 / 1-2期
关键词：
D O I：
10.1080/07328318708056192
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
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页码：197 / 207
页数：11
相关论文
共 47 条
[1]   5-SUBSTITUTED 2'-DEOXYURIDINES - CORRELATION BETWEEN INHIBITION OF TUMOR-CELL GROWTH AND INHIBITION OF THYMIDINE KINASE AND THYMIDYLATE SYNTHETASE [J].
BALZARINI, J ;
DECLERCQ, E ;
MERTES, MP ;
SHUGAR, D ;
TORRENCE, PF .
BIOCHEMICAL PHARMACOLOGY, 1982, 31 (22) :3673-3682
[2]  
BALZARINI J, 1986, UNPUB
[3]   SYNTHESIS, STRUCTURE, AND ANTITUMOR AND ANTIVIRAL ACTIVITIES OF A SERIES OF 5-HALOURIDINE CYCLIC 3',5'-MONOPHOSPHATES [J].
BERES, J ;
BENTRUDE, WG ;
KALMAN, A ;
PARKANYI, L ;
BALZARINI, J ;
DECLERCQ, E .
JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (04) :488-493
[4]   SYNTHESIS AND ANTITUMOR AND ANTIVIRAL PROPERTIES OF 5-HALO-2'-DEOXYURIDINE 3',5'-CYCLIC MONOPHOSPHATES AND "5-(TRIFLUOROMETHYL)-2'-DEOXYURIDINE 3',5'-CYCLIC MONOPHOSPHATES AND NEUTRAL TRIESTERS [J].
BERES, J ;
SAGI, G ;
BENTRUDE, WG ;
BALZARINI, J ;
DECLERCQ, E ;
OTVOS, L .
JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (07) :1243-1249
[5]   SYNTHESIS AND ANTITUMOR AND ANTIVIRAL PROPERTIES OF 5-ALKYL-2'-DEOXYURIDINES, 3',5'-CYCLIC MONOPHOSPHATES, AND NEUTRAL CYCLIC TRIESTERS [J].
BERES, J ;
BENTRUDE, WG ;
BALZARINI, J ;
DECLERCQ, E ;
OTVOS, L .
JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (04) :494-499
[6]  
BERNAERTS R, 1987, NUCLEOS NUC, V6, P721
[7]   ROLES OF THYMIDYLATE SYNTHETASE-ACTIVITY IN HERPES-SIMPLEX VIRUS-INFECTED HELA-CELLS [J].
CHENG, YC ;
NAKAYAMA, K ;
GRILL, SP .
BIOCHEMICAL PHARMACOLOGY, 1983, 32 (08) :1407-1410
[8]   ROLE OF ADENOSINE KINASE IN THE BIOLOGICAL (ANTIVIRAL AND ANTICELLULAR) ACTIVITIES OF ADENOSINE-ANALOGS [J].
COOLS, M ;
DECLERCQ, E ;
DRACH, JC .
NUCLEOSIDES & NUCLEOTIDES, 1987, 6 (1-2) :423-424
[9]   (S)-9-(2,3-DIHYDROXYPROPYL)ADENINE - ALIPHATIC NUCLEOSIDE ANALOG WITH BROAD-SPECTRUM ANTI-VIRAL ACTIVITY [J].
DECLERCQ, E ;
DESCAMPS, J ;
DESOMER, P .
SCIENCE, 1978, 200 (4341) :563-565
[10]  
DECLERCQ E, 1985, J BIOL CHEM, V260, P621
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