IS REJECTION A DIFFUSE OR LOCALIZED PROCESS IN SMALL-BOWEL TRANSPLANTATION

被引：9

作者：

GURAKAR, A ^{[1
]}

FAGIUOLI, S ^{[1
]}

HASSANEIN, T ^{[1
]}

WRIGHT, HI ^{[1
]}

BALKAN, M ^{[1
]}

FREZZA, E ^{[1
]}

TODO, S ^{[1
]}

STARZL, TE ^{[1
]}

VANTHIEL, DH ^{[1
]}

机构：

[1] UNIV PITTSBURGH,MED CTR,PITTSBURGH TRANSPLANTAT INST,PITTSBURGH,PA 15213

来源：

SURGICAL ENDOSCOPY-ULTRASOUND AND INTERVENTIONAL TECHNIQUES | 1994年 / 8卷 / 07期

关键词：

SMALL-BOWEL TRANSPLANTATION; ILEOSCOPY; BIOPSY; ACUTE CELLULAR REJECTION; INTESTINAL REJECTION;

D O I：

10.1007/BF00593436

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Utilization of endoscopy to both visualize and selectively biopsy an intestinal allograft has become the standard for early recognition and treatment of intestinal allograft rejection. Despite the widespread acceptance of the need for selective mucosal biopsies, it has not been shown that the histological features of intestinal allograft rejection are either localized or occur as part of a more diffuse phenomenon within a tubular allograft. To resolve these issues, 88 ileoscopies were performed in 12 small-bowel allograft recipients and mucosal biopsy samples were obtained at 5, 10, and 15 cm, respectively, from the ileal stoma. Each mucosal biopsy was labeled, processed, and evaluated individually for the presence and severity of any evidence for allograft rejection. The data obtained suggest that intestinal allograft rejection is a diffuse process, and biopsies obtained randomly from an ileal graft are likely to demonstrate evidence of allograft rejection when such is present.

引用

页码：762 / 764

页数：3

共 12 条

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