BIOACTIVE PRINCIPLES FROM THE ROOTS OF LINDERA-MEGAPHYLLA

被引：34

作者：

CHEN, CC ^{[1
]}

HUANG, YL ^{[1
]}

OU, JC ^{[1
]}

SU, MJ ^{[1
]}

YU, SM ^{[1
]}

TENG, CM ^{[1
]}

机构：

[1] NATL TAIWAN UNIV, COLL MED, INST PHARMACOL, TAIPEI, TAIWAN

来源：

PLANTA MEDICA | 1991年 / 57卷 / 05期

关键词：

LINDERA-MEGAPHYLLA; D-DICENTRINE; ANTIPLATELET AGGREGATION; VASORELAXANT; ANTIARRHYTHMIC ACTIVITY;

D O I：

10.1055/s-2006-960135

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

d-Dicentrine was isolated from the root of Lindera megaphylla. It inhibited the aggregation of washed rabbit platelets induced by ADP, collagen, arachidonic acid, and PAF. It also inhibited the high potassium- and norepinephrine-induced contraction of rat thoracic aorta. In rat ventricular cells treated with 3-mu-M d-dicentrine, the action potential duration (ADP50) was prolonged from 59.9 +/- 1.3 msec to 201 +/- 28.7 msec.

引用

页码：406 / 408

页数：3

共 7 条

[1]

CHEN CC, 1988, CHINESE PHARM J, V40, P15

[2] STUDIES ON ALKALOIDS OF FORMOSAN LAURACEOUS PLANTS .15. ALKALOIDS OF LINDERA-OLDHAMII HEMSL [J].

LU, ST ;

LIN, LC ;

LIN, CM ;

WANG, SJ ;

LAI, PH .

YAKUGAKU ZASSHI, 1972, 92 (07) :910-&

[3] A UNIFORM ENZYMATIC METHOD FOR DISSOCIATION OF MYOCYTES FROM HEARTS AND STOMACHS OF VERTEBRATES [J].

MITRA, R ;

MORAD, M .

AMERICAN JOURNAL OF PHYSIOLOGY, 1985, 249 (05) :1056-1060

[4]

OBRIEN JR, 1962, J CLIN PATHOL, V15, P452

[5] INHIBITION OF THROMBIN-INDUCED AND COLLAGEN-INDUCED PHOSPHOINOSITIDES BREAKDOWN IN RABBIT PLATELETS BY A PAF ANTAGONIST DENUDATIN-B, AN ISOMER OF KADSURENONE [J].

TENG, CM ;

YU, SM ;

CHEN, CC ;

HUANG, YL ;

HUANG, TF .

THROMBOSIS RESEARCH, 1990, 59 (01) :121-130

[6] 2 ANTIPLATELET AGENTS FROM MAGNOLIA-OFFICINALIS [J].

TENG, CM ;

CHEN, CC ;

KO, FN ;

LEE, LG ;

HUANG, TF ;

CHEN, YP ;

HSU, HY .

THROMBOSIS RESEARCH, 1988, 50 (06) :757-765

[7]

TENG CM, 1987, BIOCHIM BIOPHYS ACTA, V924, P375

← 1 →