ISOQUINOLINE ALKALOIDS FROM NEOLITSEA-KONISHII

被引：34

作者：

LEE, SS ^{[1
]}

YANG, HC ^{[1
]}

机构：

[1] NATL RES INST CHINESE MED,TAIPEI,TAIWAN

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 1992年 / 39卷 / 02期

关键词：

NEOLISEA-KONISHII; CPC; ISOQUINOLINE-ALKALOIDS; APORHINES; C-13; NMR; N-METHYLATION SHIFT; BENZYLISOQUINOLINE; PROAPORPHINES; MORPHINAN; CHEMOTAXONOMY;

D O I：

10.1002/jccs.199200031

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

By combination of centrifugal partition chromatography (CPC) and common separation methods, twelve known bases were isolated and characterized from the first chemical investigation of Neolitsea konishii (H.) K. & S.. They belong to isoquinoline alkaloids of four types: eight aporphines, nornuciferine (1), N-methyllaurotetanine (2), laurolitsine (3), boldine (4), laurotetanine (5), isoboldine (6), actinodaphine (7) and corytuberine (8); two proaporphines, stepharine (9) and glaziovine (10); one benzylisoquinoline, reticuline (11); and one morphinan, pallidine (12). Among these, compounds 3, 6 and 11 are abundant and will be modified for pharmacological tests. The content of various alkaloids in the plant is useful as a basis for chemotaxonomy.

引用

页码：189 / 194

页数：6

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