PROSTAGLANDIN-E1 FOR THE TREATMENT OF PRIMARY NON-FUNCTION OF THE DONOR ORGAN IN LIVER-TRANSPLANTATION

被引:7
作者
MOLLISON, LC [1 ]
ANGUS, PW [1 ]
JONES, RM [1 ]
机构
[1] AUSTIN HOSP,LIVER TRANSPLANT UNIT,STUDLEY RD,HEIDELBERG,VIC 3084,AUSTRALIA
关键词
PRESERVATION;
D O I
10.5694/j.1326-5377.1991.tb116384.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To present a case in which acute failure of a liver graft was treated with an infusion of prostaglandin E1 (PGE1). Clinical features: A nine-year-old girl underwent liver transplantation for Wilson's disease. Her course was complicated by primary non-function of the graft as evidenced by poor bile production, rising bilirubin and liver enzyme levels and a severe coagulopathy. Intervention and outcome: PGE1 was infused and there was recovery of graft function. The need for urgent re-transplantation was avoided. Conclusions: PGE1 may have an important role in liver transplantation considering the logistic difficulties of obtaining donor livers for urgent transplantation in Australia.
引用
收藏
页码:51 / 53
页数:3
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