OVARIAN LOCALIZATION BY EMBRYONAL TERATOCARCINOMA CELLS DERIVED FROM FEMALE GERM-CELLS

被引：21

作者：

KAHAN, B

机构：

[1] Zoology Department, University of Wisconsin, Madison, 53706, Wisconsin

来源：

SOMATIC CELL GENETICS | 1979年 / 5卷 / 06期

关键词：

D O I：

10.1007/BF01542640

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Embryonal carcinoma cells derived from several different spontaneous ovarian teratocarcinomas of strain LT mice form tumors that are located exclusively, in many cases, in the ovaries of female mice. Embryonal cells previously unselected for site specificity localize in the ovaries regardless of route of entry of the cells, and produce very few tumors in males following intraperitoneal injections. The ovary tumors have been verified as originating from the injected cells by chromosomal and drug resistance markers, as well as by general in vitro growth characteristics. Cell-cell adhesion studies suggest specificity at the level of tumor cell-ovary organ cell interaction. © 1979 Plenum Publishing Corporation.

引用

页码：763 / 780

页数：18

共 47 条

[1] LOCALIZATION AND SYNTHESIS OF SOME COLLAGEN TYPES IN DEVELOPING MOUSE EMBRYOS [J].