RATIONAL DESIGN OF POTENT NONPEPTIDAL HIV PROTEASE INHIBITORS

被引:0
|
作者
GHOSH, AK
CHEN, Y
XU, YB
CHO, WH
BUTHOD, J
HOLLAND, LE
WALTERS, DE
机构
[1] UNIV ILLINOIS,CHICAGO,IL 60680
[2] IIT,RES INST,DEPT LIFE SCI,CHICAGO,IL 60616
[3] FINCH UNIV HLTH SCI,CHICAGO MED SCH,DEPT BIOL CHEM,N CHICAGO,IL
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:27 / MEDI
相关论文
共 50 条
  • [21] From nonpeptide toward noncarbon protease inhibitors:: Metallacarboranes as specific and potent inhibitors of HIV protease
    Cígler, P
    Kozísek, M
    Rezácová, P
    Brynda, J
    Otwinowski, Z
    Pokorná, J
    Plesek, J
    Grüner, B
    Dolecková-Maresová, L
    Mása, M
    Sedlácek, J
    Bodem, J
    Kräusslich, HG
    Král, V
    Konvalinka, J
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (43) : 15394 - 15399
  • [22] Interactions of ligands with macromolecules: Rational design of specific inhibitors of aspartic protease of HIV-1
    Frecer, V
    Miertus, S
    MACROMOLECULAR CHEMISTRY AND PHYSICS, 2002, 203 (10-11) : 1650 - 1657
  • [23] Substrate envelope based design of potent HIV-1 protease inhibitors resilient to resistance
    Nalam, M. N. L.
    Ali, A.
    Reddy, G. S. K. K.
    Anjum, S. G.
    Rana, T. M.
    Schiffer, C. A.
    ANTIVIRAL THERAPY, 2010, 15 : A15 - A15
  • [24] Rational Design of Potent Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase
    Chong, Pek
    Sebahar, Paul
    Youngman, Michael
    Garrido, Dulce
    Zhang, Huichang
    Stewart, Eugene L.
    Nolte, Robert T.
    Wang, Liping
    Ferris, Robert G.
    Edelstein, Mark
    Weaver, Kurt
    Mathis, Amanda
    Peat, Andrew
    JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (23) : 10601 - 10609
  • [25] Synthesis of potent and orally active HIV-protease inhibitors
    Capraro, HG
    Bold, G
    Fassler, A
    Cozens, R
    Klimkait, T
    Lazdins, J
    Poncioni, B
    Rosel, JL
    Stover, D
    Lang, M
    ARCHIV DER PHARMAZIE, 1996, 329 (06) : 273 - 278
  • [26] 4-HYDROXYCOUMARIN-DERIVED, POTENT HIV PROTEASE INHIBITORS
    TURNER, SR
    STROHBACH, JW
    TOMICH, PK
    WATENPAUGH, KD
    HOWE, WJ
    DOLAK, LA
    CHONG, KT
    RUWART, MJ
    ZIPP, GL
    SCHWENDE, FJ
    PADBURY, GE
    THAISRIVONGS, S
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 208 : 15 - MEDI
  • [27] Design of translactam HCMV protease inhibitors as potent antivirals
    Borthwick, AD
    MEDICINAL RESEARCH REVIEWS, 2005, 25 (04) : 427 - 452
  • [28] Rational design and synthesis of highly potent β-glucocerebrosidase inhibitors
    Zhu, XX
    Sheth, KA
    Li, SH
    Chang, HH
    Fan, JQ
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (45) : 7450 - 7453
  • [29] A RATIONAL APPROACH IN THE SEARCH FOR POTENT INHIBITORS AGAINST HIV PROTEINASE
    HUI, KY
    MANETTA, JV
    GYGI, T
    BOWDON, BJ
    KEITH, KA
    SHANNON, WM
    LAI, MHT
    FASEB JOURNAL, 1991, 5 (11): : 2606 - 2610
  • [30] Additivity in the Analysis and Design of HIV Protease Inhibitors
    Jorissen, Robert N.
    Reddy, G. S. Kiran Kumar
    Ali, Akbar
    Altman, Michael D.
    Chellappan, Sripriya
    Anjum, Saima G.
    Tidor, Bruce
    Schiffer, Celia A.
    Rana, Tariq M.
    Gilson, Michael K.
    JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (03) : 737 - 754