SELECTIVE SYNTHESIS OF ENETHIOLS

被引：17

作者：

LENOCHER, AM ^{[1
]}

METZNER, P ^{[1
]}

机构：

[1] INST SCI MAT & RAYONNEMENT,CHIM COMPOSES THIO ORGAN LAB,CNRS,6 BLVD MARECHAL JUIN,F-14050 CAEN,FRANCE

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(00)60029-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tautomerically pure aliphatic thioketones 3 have been prepared by treatment of dimethyl acetals with hydrogen sulfide in the presence of zinc chloride. Deprotonation with LDA leads to Z enethiolates 4 which were S-silylated with trimethylsilyl chloride to give silyl vinyl sulfides 5. Methanolysis of 5 quantitatively affords enethiols 1, devoid of the isomeric thioketones 3.

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页码：6151 / 6154

页数：4

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