USE OF THE INTERNAL AND EXTERNAL STANDARD TECHNIQUES IN DETERMINATIONS OF AMINO-ACIDS BY ION-EXCHANGE CHROMATOGRAPHY

Influence of the internal standard technique on the precision of amino acid determination was studied. The law of propagation of errors and the information theory was applied in this paper. From the results it follows that the internal standard technique did not inevitably improve the precision of the determination. In the case of a multicomponent sample, the external standard technique improved the accuracy only if calibration curve was used.