ADRENOCORTICOTROPIN-CORTISOL AXIS ABNORMALITIES IN HEMODIALYSIS PATIENTS

被引：54

作者：

MCDONALD, WJ ^{[1
]}

GOLPER, TA ^{[1
]}

MASS, RD ^{[1
]}

KENDALL, JW ^{[1
]}

PORTER, GA ^{[1
]}

GIRARD, DE ^{[1
]}

FISCHER, MD ^{[1
]}

机构：

[1] UNIV OREGON, HLTH SCI CTR, PORTLAND, OR 97201 USA

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1979年 / 48卷 / 01期

关键词：

D O I：

10.1210/jcem-48-1-92

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The ACTH-cortisol axis was studied in 15 hemodialysis patients. Basal plasma cortisol concentrations were found to be elevated and ACTH to be in the high normal range. Cortisol responded normally to exogenous ACTH, but neither cortisol nor ACTH were suppressed in response to oral dexamethasone. 11-Deoxycortisol and ACTH concentrations did not rise normally in response to either oral or iv metyrapone. We conclude that standard testing of the ACTH-cortisol axis in dialysis patients yields results suggesting Cushing's syndrome. © 1979 by The Endocrine Society.

引用

页码：92 / 95

页数：4

共 18 条

[1]

AKMAL M, 1977, T AM SOC ART INT ORG, V23, P703

[2] PITUITARY AND PLASMA LIPOTROPINS - DEMONSTRATION OF ARTIFACTUAL NATURE OF BETAMSH [J].