LOW-DOSE AND HIGH-DOSE INTRAVENOUS INSULIN THERAPY FOR DIABETIC KETOACIDOSIS

被引：2

作者：

GONZALEZVILLALPANDO, C ^{[1
]}

BLACHLEY, JD ^{[1
]}

VAUGHAN, GM ^{[1
]}

SMITH, JD ^{[1
]}

机构：

[1] UNIV TEXAS, HLTH SCI CTR, DEPT INTERNAL MED, DIV ENDOCRINOL, SAN ANTONIO, TX 78284 USA

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 1979年 / 241卷 / 09期

关键词：

D O I：

10.1001/jama.241.9.925

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Low-dose continuous insulin infusion was compared with a conventional high-dose i.v. bolus method of insulin administration in 18 episodes of diabetic ketoacidosis. The average rate of reduction in serum glucose concentration was 9.5 .+-. 3.8%/h in the continuous infusion group and 10.7 .+-. 4.7%/h in the bolus group. Arterial blood pH was corrected to 7.35 by 9.9 .+-. 2.6/h in the continuous infusion group and by 10.4 .+-. 3.2/h in the bolus group. The above means are not significantly different between groups. By the time pH was corrected to 7.35, patients in the continuous infusion group had received 121 .+-. 44 units of insulin, whereas those in the bolus group had received 326 .+-. 152 units. The continuous low-dose insulin infusion method is as safe and efficacious as the conventional high-dose i.v. bolus method.

引用

页码：925 / 927

页数：3

共 50 条

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