NITRIC-OXIDE PRODUCTION BY HUMAN MONOCYTES - EVIDENCE FOR A ROLE OF CD23

被引：171

作者：

DUGAS, B

MOSSALAYI, MD

DAMAIS, C

KOLB, JP

机构：

[1] CTR CORDELIERS, INSERM, U313, F-75006 PARIS, FRANCE

[2] INST CURIE, INSERM, U365, F-75005 PARIS, FRANCE

来源：

IMMUNOLOGY TODAY | 1995年 / 16卷 / 12期

基金：

澳大利亚研究理事会;

关键词：

D O I：

10.1016/0167-5699(95)80080-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Nitric oxide (NO) appears to be an important and pleiotropic bioregulator of immune responses. The existence of the NO synthase (NOS) pathway in human monocytes/macrophages remains a subject of controversy, despite an increasing number of reports suggesting that human monocytes produce NO in vitro in response to various stimuli. Here, Bernard Dugas and colleagues consider the arguments supporting these conclusions, with particular emphasis on the results obtained by ligation of the low-affinity IgE-receptor (Fc epsilon RIIb/CD23b).

引用

页码：574 / 580

页数：7