CHIRAL SYNTHESIS OF LIGNAN LACTONES, (-)-HINOKININ, (-)-DEOXYPODORHIZONE, (-)-ISOHIBALACTONE AND (-)-SAVININ BY MEANS OF ENANTIOSELECTIVE DEPROTONATION STRATEGY

被引：49

作者：

HONDA, T ^{[1
]}

KIMURA, N ^{[1
]}

SATO, S ^{[1
]}

KATO, D ^{[1
]}

TOMINAGA, H ^{[1
]}

机构：

[1] JPS PHARMACEUT CO LTD, HAGA, TOCHIGI 32133, JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 08期

关键词：

D O I：

10.1039/p19940001043

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral synthesis of lignan lactones, (-)-hinokinin, (-)-deoxypodorhizone, (-)-isohibalactone and (-)-savinin, has been achieved by employing an enantioselective deprotonation of 3-(3,4-methylene-dioxybenzyl)cyclobutanone with lithium (S.S')-alpha,alpha'-dimethyldibenzylamide, as a key step.

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页码：1043 / 1046

页数：4

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