THE EXPRESSION OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) MESSENGER-RNA IN RAT-BRAIN - POSSIBLE ROLE OF ENDOGENOUS PACAP IN VASOPRESSIN RELEASE

被引：28

作者：

MURASE, T

KONDO, K

ARIMA, H

IWASAKI, Y

ITO, M

MIURA, Y

OISO, Y

机构：

[1] First Department of Internal Medicine, Nagoya University School of Medicine, Nagoya

来源：

NEUROSCIENCE LETTERS | 1995年 / 185卷 / 02期

关键词：

PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP); VASOPRESSIN; MESSENGER-RNA; IN SITU HYBRIDIZATION; DEHYDRATION; ARCUATE NUCLEUS;

D O I：

10.1016/0304-3940(94)11235-B

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We investigated the expression of pituitary adenylate cyclase-activating polypeptide (PACAP) mRNA in rat brain by in situ hybridization. PACAP mRNA was prominently expressed in arcuate nucleus (ARC). Three days of water deprivation significantly increased plasma arginine vasopressin and markedly potentiated the expression of PACAP mRNA in ARC. These results suggest that PACAP in ARC may play some physiological role, possibly one of which may be the control of vasopressin

引用

页码：103 / 106

页数：4