DIFFUSION OR AUTOCATALYSIS OF RETINOIC ACID CANNOT EXPLAIN PATTERN-FORMATION IN THE CHICK WING BUD

被引：4

作者：

PAPAGEORGIOU, S

ALMIRANTIS, Y

机构：

[1] Nrc “Demokritos, ”, Athens, Aghia Paraskevi

来源：

DEVELOPMENTAL DYNAMICS | 1992年 / 194卷 / 04期

关键词：

RETINOIC ACID; CHICK LIMB DEVELOPMENT; MORPHOGEN DIFFUSION; AUTOCATALYSIS; REACTION DIFFUSION;

D O I：

10.1002/aja.1001940404

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

We have collected several experimental data of pattern duplications due to the ZPA transplantation or application of retinoic acid on the developing chick limb bud. We have compared these data with the predictions of models based on diffusion or autocatalysis of retinoids. It turns out that these models cannot comprehensively explain the data. More specifically, retinoic acid cannot be either diffusing from a ZPA source or participate in an autocatalytic gradient formation.

引用

页码：282 / 288

页数：7

共 33 条

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ALLEN F, 1990, DEVELOPMENT, V108, P623

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