CLOMID ADMINISTRATION TO PREGNANT RATS CAUSES ABNORMALITIES OF THE REPRODUCTIVE-TRACT IN OFFSPRING AND MOTHERS

被引：41
|
作者：
MCCORMACK, S
CLARK, JH
机构：
来源：
SCIENCE | 1979年 / 204卷 / 4393期
关键词：
D O I：
10.1126/science.432668
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In rats, a single injection of clomiphene citrate (Clomid) during pregnancy causes multiple abnormalities of the reproductive tract in the offspring and mothers. These abnormalities probably result from the ability of Clomid to cause long-term estrogenic stimulation. Clomiphene citrate (Clomid) is used extensively for the induction of ovulation in women with secondary amenorrhea.
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页码：629 / 631
页数：3
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